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Efficacy of anti-insulin like growth factor I receptor (IGF-IR) monoclonal antibody cixutumumab in mesothelioma is highly correlated with IGF-IR sites/cell

Insulin growth factor-I receptor (IGF-IR) is expressed in mesothelioma and therefore an attractive target for therapy. The anti-tumor activity of cixutumumab, a humanized monoclonal antibody to IGF-IR, in mesothelioma and relationship to IGF-IR expression was investigated using eight early passage t...

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Hlavní autoři: Kalra, Neetu, Zhang, Jingli, Yu, Yunkai, Ho, Mitchell, Merino, Maria, Cao, Liang, Hassan, Raffit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371100/
https://ncbi.nlm.nih.gov/pubmed/22323052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27471
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