Pharmacokinetics of Ferroquine, a Novel 4-Aminoquinoline, in Asymptomatic Carriers of Plasmodium falciparum Infections

Ferroquine (SSR97193), a ferrocene-quinoline conjugate, is a promising novel antimalarial currently undergoing clinical evaluation. This study characterizes its pharmacokinetic properties. Young male African volunteers with asymptomatic Plasmodium falciparum infection were administered a single oral...

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Hlavní autoři: Supan, Christian, Mombo-Ngoma, Ghyslain, Dal-Bianco, Matthias P., Ospina Salazar, Carmen L., Issifou, Saadou, Mazuir, Florent, Filali-Ansary, Aziz, Biot, Christophe, Ter-Minassian, Daniel, Ramharter, Michael, Kremsner, Peter G., Lell, Bertrand
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370764/
https://ncbi.nlm.nih.gov/pubmed/22430976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05359-11
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