Phase I randomized dose-ascending placebo-controlled trials of ferroquine - a candidate anti-malarial drug - in adults with asymptomatic Plasmodium falciparum infection

BACKGROUND: The development and spread of drug resistant Plasmodium falciparum strains is a major concern and novel anti-malarial drugs are, therefore, needed. Ferroquine is a ferrocenic derivative of chloroquine with proven anti-malarial activity against chloroquine-resistant and -sensitive P. falc...

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Autors principals: Mombo-Ngoma, Ghyslain, Supan, Christian, Dal-Bianco, Matthias P, Missinou, Michel A, Matsiegui, Pierre-Blaise, Ospina Salazar, Carmen L, Issifou, Saadou, Ter-Minassian, Daniel, Ramharter, Michael, Kombila, Maryvonne, Kremsner, Peter G, Lell, Bertrand
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056844/
https://ncbi.nlm.nih.gov/pubmed/21362162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-53
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