A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon

BACKGROUND: Chloroquine resistance (CR) decreased after the removal of chloroquine from national treatment guidelines in Malawi, Kenia and Tanzania. In this investigation the prevalence of the chloroquine resistance (CQR) conferring mutant pfcrt allele and its associated chromosomal haplotype were d...

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Detalhes bibliográficos
Main Authors: Frank, Matthias, Lehners, Nicola, Mayengue, Pembe I, Gabor, Julian, Dal-Bianco, Matthias, Kombila, David U, Ngoma, Ghyslain Mombo, Supan, Christian, Lell, Bertrand, Ntoumi, Francine, Grobusch, Martin P, Dietz, Klaus, Kremsner, Peter G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215978/
https://ncbi.nlm.nih.gov/pubmed/22004584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-304
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