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Effect of HIV-1 Infection and Sex on the Cellular Pharmacology of the Antiretroviral Drugs Zidovudine and Lamivudine

The cellular pharmacology of zidovudine (ZDV) and lamivudine (3TC) in vivo is not completely understood. This prospective longitudinal study investigated the relationship between HIV-1 serostatus, sex, race, and time on therapy with intracellular and plasma ZDV and 3TC concentrations. Of 20 HIV-sero...

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Main Authors: Rower, Joseph E., Meditz, Amie, Gardner, Edward M., Lichtenstein, Kenneth, Predhomme, Julie, Bushman, Lane R., Klein, Brandon, Zheng, Jia-Hua, MaWhinney, Samantha, Anderson, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370731/
https://ncbi.nlm.nih.gov/pubmed/22391541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06337-11
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