Ingested Human Insulin Inhibits the Mosquito NF-κB-Dependent Immune Response to Plasmodium falciparum

We showed previously that ingested human insulin activates the insulin/IGF-1 signaling pathway in Anopheles stephensi and increases the susceptibility of these mosquitoes to Plasmodium falciparum. In other organisms, insulin can alter immune responsiveness through regulation of NF-κB transcription f...

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Autori principali: Pakpour, Nazzy, Corby-Harris, Vanessa, Green, Gabriel P., Smithers, Hannah M., Cheung, Kong W., Riehle, Michael A., Luckhart, Shirley
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370580/
https://ncbi.nlm.nih.gov/pubmed/22473605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00024-12
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