A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated by Sertoli and peritubular myoid cells, but their relative roles and the mechanisms involved remain largely unknown. Using Cre/loxP technolog...

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Detalhes bibliográficos
Main Authors: De Gendt, Karel, Swinnen, Johannes V., Saunders, Philippa T. K., Schoonjans, Luc, Dewerchin, Mieke, Devos, Ann, Tan, Karen, Atanassova, Nina, Claessens, Frank, Lécureuil, Charlotte, Heyns, Walter, Carmeliet, Peter, Guillou, Florian, Sharpe, Richard M., Verhoeven, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337052/
https://ncbi.nlm.nih.gov/pubmed/14745012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308114100
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