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Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

Human neonates infected with herpes simplex virus 1 (HSV-1) develop one of three distinct patterns of infection: (i) infection limited to the skin, eye or mouth; (ii) infection of the CNS; or (iii) disseminated infection. The disseminated form usually involves the liver, adrenal gland, and lung, and...

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Autori principali: Kurt-Jones, Evelyn A., Chan, Melvin, Zhou, Shenghua, Wang, Jennifer, Reed, George, Bronson, Roderick, Arnold, Michelle M., Knipe, David M., Finberg, Robert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC337050/
https://ncbi.nlm.nih.gov/pubmed/14739339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308057100
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