Complement regulation at the molecular level: The structure of decay-accelerating factor

The human complement regulator CD55 is a key molecule protecting self-cells from complement-mediated lysis. X-ray diffraction and analytical ultracentrifugation data reveal a rod-like arrangement of four short consensus repeat (SCR) domains in both the crystal and solution. The stalk linking the fou...

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Autori principali: Lukacik, P., Roversi, P., White, J., Esser, D., Smith, G. P., Billington, J., Williams, P. A., Rudd, P. M., Wormald, M. R., Harvey, D. J., Crispin, M. D. M., Radcliffe, C. M., Dwek, R. A., Evans, D. J., Morgan, B. P., Smith, R. A. G., Lea, S. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC337044/
https://ncbi.nlm.nih.gov/pubmed/14734808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307200101
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