Biological activity, membrane-targeting modification, and crystallization of soluble human decay accelerating factor expressed in E. coli

Decay-accelerating factor (DAF, CD55) is a glycophosphatidyl inositol-anchored glycoprotein that regulates the activity of C3 and C5 convertases. In addition to understanding the mechanism of complement inhibition by DAF through structural studies, there is also an interest in the possible therapeut...

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Bibliographische Detailangaben
Hauptverfasser: White, Jennifer, Lukacik, Petra, Esser, Dirk, Steward, Michael, Giddings, Naomi, Bright, Jeremy R., Fritchley, Sarah J., Morgan, B. Paul, Lea, Susan M., Smith, Geoffrey P., Smith, Richard A.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2280017/
https://ncbi.nlm.nih.gov/pubmed/15322283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03455604
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