Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells

MCF10A mammary epithelial cells form growth-arrested structures when cultured in three-dimensional basement membrane gels. Activation of the receptor tyrosine kinase ErbB2 induces formation of proliferative structures that share properties with noninvasive early stage lesions. We conducted a genetic...

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Hlavní autoři: Seton-Rogers, Sarah E., Lu, Yu, Hines, Lisa M., Koundinya, Malvika, LaBaer, Joshua, Muthuswamy, Senthil K., Brugge, Joan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC337040/
https://ncbi.nlm.nih.gov/pubmed/14739340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308090100
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