Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells

MCF10A mammary epithelial cells form growth-arrested structures when cultured in three-dimensional basement membrane gels. Activation of the receptor tyrosine kinase ErbB2 induces formation of proliferative structures that share properties with noninvasive early stage lesions. We conducted a genetic...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Seton-Rogers, Sarah E., Lu, Yu, Hines, Lisa M., Koundinya, Malvika, LaBaer, Joshua, Muthuswamy, Senthil K., Brugge, Joan S.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2004
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC337040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14739340/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308090100
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