Regulation of Protein Kinase C-related Protein Kinase 2 (PRK2) by an Intermolecular PRK2-PRK2 Interaction Mediated by Its N-terminal Domain

Protein kinase C-related protein kinases (PRKs) are effectors of the Rho family of small GTPases and play a role in the development of diseases such as prostate cancer and hepatitis C. Here we examined the mechanism underlying the regulation of PRK2 by its N-terminal region. We show that the N-termi...

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Detalhes bibliográficos
Main Authors: Bauer, Angelika F., Sonzogni, Silvina, Meyer, Lucas, Zeuzem, Stefan, Piiper, Albrecht, Biondi, Ricardo M., Neimanis, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370243/
https://ncbi.nlm.nih.gov/pubmed/22511787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.327437
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