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ACE2, the Receptor that Enables Infection by SARS‐CoV‐2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators

Angiotensin converting enzyme 2 (ACE2) is the human receptor that interacts with the spike protein of coronaviruses, including the one that produced the 2020 coronavirus pandemic (COVID‐19). Thus, ACE2 is a potential target for drugs that disrupt the interaction of human cells with SARS‐CoV‐2 to abo...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Gross, Lissy Z. F., Sacerdoti, Mariana, Piiper, Albrecht, Zeuzem, Stefan, Leroux, Alejandro E., Biondi, Ricardo M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405163/
https://ncbi.nlm.nih.gov/pubmed/32663362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000368
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