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Directed Evolution of Lectins with Sugar-binding Specificity for 6-Sulfo-galactose

6-sulfo-galactose (6S-Gal) is a prevalent motif observed in highly sulfated keratan sulfate, which is closely associated with the glioblastoma malignancy while acting as a critical determinant for endogenous lectins. However, facile detection of this unique glycoepitope is greatly hampered because o...

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Autores principales: Hu, Dan, Tateno, Hiroaki, Kuno, Atsushi, Yabe, Rikio, Hirabayashi, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370213/
https://ncbi.nlm.nih.gov/pubmed/22493425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351965
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