Protein Kinase C-δ Negatively Regulates T Cell Receptor-induced NF-κB Activation by Inhibiting the Assembly of CARMA1 Signalosome

T-cell receptor (TCR)-induced T-cell activation is a critical event in adaptive immune responses. The engagement of TCR complex by antigen along with the activation of the costimulatory receptors trigger a cascade of intracellular signaling, in which caspase recruitment domain-containing membrane-as...

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Detalhes bibliográficos
Main Authors: Liu, Yu, Song, Ren, Gao, Yan, Li, Yi, Wang, Shuai, Liu, Hai-Yun, Wang, Yan, Hu, Yun-Hong, Shu, Hong-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370191/
https://ncbi.nlm.nih.gov/pubmed/22528498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.335463
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