Estradiol Protects Dermal Hyaluronan/Versican Matrix during Photoaging by Release of Epidermal Growth Factor from Keratinocytes

Hyaluronan (HA) and versican are key components of the dermis and are responsive to ultraviolet (UV)B-induced remodeling. The aim of this study was to explore the molecular mechanisms mediating the effects of estrogen (E(2)) on HA-rich extracellular matrix during photoaging. Hairless skh-1 mice were...

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Detalhes bibliográficos
Main Authors: Röck, Katharina, Meusch, Michael, Fuchs, Nikola, Tigges, Julia, Zipper, Petra, Fritsche, Ellen, Krutmann, Jean, Homey, Bernhard, Reifenberger, Julia, Fischer, Jens W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370189/
https://ncbi.nlm.nih.gov/pubmed/22493503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353151
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