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Chaperone gp96-independent Inhibition of Endotoxin Response by Chaperone-based Peptide Inhibitors

HSP90 chaperones a large number of proteins, and it plays essential roles in multiple signaling pathways to maintain protein homeostasis in the cytosol. In addition, HSP90 has been implicated in mediating recognition of lipopolysaccharide (LPS). However, no pharmacologic agents have been developed t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Shuang, Dole, Krystal, Hong, Feng, Noman, Abu Shadat M., Issacs, Jennifer, Liu, Bei, Li, Zihai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370174/
https://ncbi.nlm.nih.gov/pubmed/22532561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343848
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