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Chaperone gp96-independent Inhibition of Endotoxin Response by Chaperone-based Peptide Inhibitors
HSP90 chaperones a large number of proteins, and it plays essential roles in multiple signaling pathways to maintain protein homeostasis in the cytosol. In addition, HSP90 has been implicated in mediating recognition of lipopolysaccharide (LPS). However, no pharmacologic agents have been developed t...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370174/ https://ncbi.nlm.nih.gov/pubmed/22532561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343848 |
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