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15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity
Granulysin is expressed as two isoforms by human cytotoxic cells: a single mRNA gives rise to 15 kDa granulysin, a portion of which is cleaved to a 9 kDa protein. Studies with recombinant 9 kDa granulysin have demonstrated its cytolytic and proinflammatory properties, but much less is known about th...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370151/ https://ncbi.nlm.nih.gov/pubmed/22586033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200570 |
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