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Megakaryocyte progenitors are the main antigen presenting cells inducing Th17 response to lupus autoantigens and foreign antigens
In search of autoantigen presenting cells (APC) that prime pathogenic autoantibody-inducing T helper (Th) cells of lupus, we found that CD41(+)CD151(+) cells in Lineage(−) (Lin(−)) CD117+ (c-Kit(+)) CX3CR1(−) splenocytes depleted of known APCs, were most proficient in presenting nuclear autoantigens...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370101/ https://ncbi.nlm.nih.gov/pubmed/22561152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200452 |
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