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Human Herpesvirus 8 Interferon Regulatory Factor-Mediated BH3-Only Protein Inhibition via Bid BH3-B Mimicry

Viral replication efficiency is in large part governed by the ability of viruses to counteract pro-apoptotic signals induced by infection of host cells. For HHV-8, viral interferon regulatory factor-1 (vIRF-1) contributes to this process in part via inhibitory interactions with BH3-only protein (BOP...

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Detalhes bibliográficos
Main Authors: Choi, Young Bong, Sandford, Gordon, Nicholas, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369933/
https://ncbi.nlm.nih.gov/pubmed/22685405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002748
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