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MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells

MicroRNAs (miRNAs) play important roles in normal cellular differentiation and oncogenesis. microRNA93 (mir-93), a member of the mir106b-25 cluster, located in intron 13 of the MCM7 gene, although frequently overexpressed in human malignancies may also function as a tumor suppressor gene. Using a se...

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Autors principals: Liu, Suling, Patel, Shivani H., Ginestier, Christophe, Ibarra, Ingrid, Martin-Trevino, Rachel, Bai, Shoumin, McDermott, Sean P., Shang, Li, Ke, Jia, Ou, Sing J., Heath, Amber, Zhang, Kevin J., Korkaya, Hasan, Clouthier, Shawn G., Charafe-Jauffret, Emmanuelle, Birnbaum, Daniel, Hannon, Gregory J., Wicha, Max S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369932/
https://ncbi.nlm.nih.gov/pubmed/22685420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002751
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