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IKK-Dependent, NF-κB-Independent Control of Autophagic Gene Expression

The induction of mammalian autophagy, a cellular catabolic bulk-degradation process conserved from humans to yeast, was recently shown to require IKK, the upstream regulator of the NF-κB pathway. Interestingly, it was shown that this response did not involve classic NF-κB. Thus, the mechanism by whi...

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Autores principales: Comb, William C., Cogswell, Patricia, Sitcheran, Raquel, Baldwin, Albert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369814/
https://ncbi.nlm.nih.gov/pubmed/21151171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.553
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