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Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK
While NF-κB is considered to play key roles in the development and progression of many cancers, the mechanisms whereby this transcription factor is activated in cancer are poorly understood. A key oncoprotein in a variety of cancers is the serine–threonine kinase Akt, which can be activated by mutat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2418585/ https://ncbi.nlm.nih.gov/pubmed/18519641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1662308 |
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