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An Azobenzene Photoswitch Sheds Light on Turn Nucleation in Amyloid-β Self-Assembly
[Image: see text] Amyloid-β (Aβ) self-assembly into cross-β amyloid fibrils is implicated in a causative role in Alzheimer’s disease pathology. Uncertainties persist regarding the mechanisms of amyloid self-assembly and the role of metastable prefibrillar aggregates. Aβ fibrils feature a sheet-turn-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369795/ https://ncbi.nlm.nih.gov/pubmed/22860190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2001188 |
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