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Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer
[Image: see text] Aβ oligomers play a key role in the pathophysiology of Alzheimer’s disease. Research into structure−function relationships of Aβ oligomers has been hampered by the lack of large amounts of homogeneous and stable material. Using computational chemistry, we designed conservative cyst...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369749/ https://ncbi.nlm.nih.gov/pubmed/22778868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200011h |
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