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RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells

Retinoic acid (RA) induces embryonic stem cell differentiation. The effects of RA are mediated by retinoic acid receptors (RARs) that promote epigenetic changes controlling gene transcription. We show here that RARγ, in the absence of the ligand RA, is required for deposition of the histone variant...

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Hlavní autoři: Amat, Ramon, Gudas, Lorraine J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369573/
https://ncbi.nlm.nih.gov/pubmed/20857416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22420
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