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RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells

Retinoic acid (RA) induces embryonic stem cell differentiation. The effects of RA are mediated by retinoic acid receptors (RARs) that promote epigenetic changes controlling gene transcription. We show here that RARγ, in the absence of the ligand RA, is required for deposition of the histone variant...

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Bibliografische gegevens
Hoofdauteurs: Amat, Ramon, Gudas, Lorraine J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369573/
https://ncbi.nlm.nih.gov/pubmed/20857416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22420
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