Inhibition of Gene Expression of Organic Cation/Carnitine Transporter and Antioxidant Enzymes in Oxazaphosphorines-Induced Acute Cardiomyopathic Rat Models

It is well documented that high therapeutic doses of oxazaphosphorines, cyclophosphamide (CP) and ifosfamide (IFO), are associated with cardiomyopathy. This study investigated whether oxazaphosphorines alter the expression of organic cation/carnitine transporter (OCTN2) and antioxidant genes and if...

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Détails bibliographiques
Auteurs principaux: Sayed-Ahmed, Mohamed M., Aldelemy, Meshan Lafi, Hafez, Mohamed M., Al-Shabanah, Othman A.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369488/
https://ncbi.nlm.nih.gov/pubmed/22701146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/452902
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