Inhibition of Gene Expression of Organic Cation/Carnitine Transporter and Antioxidant Enzymes in Oxazaphosphorines-Induced Acute Cardiomyopathic Rat Models

It is well documented that high therapeutic doses of oxazaphosphorines, cyclophosphamide (CP) and ifosfamide (IFO), are associated with cardiomyopathy. This study investigated whether oxazaphosphorines alter the expression of organic cation/carnitine transporter (OCTN2) and antioxidant genes and if...

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Detalhes bibliográficos
Main Authors: Sayed-Ahmed, Mohamed M., Aldelemy, Meshan Lafi, Hafez, Mohamed M., Al-Shabanah, Othman A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369488/
https://ncbi.nlm.nih.gov/pubmed/22701146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/452902
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