Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis

OBJECTIVE: Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) are related chronic autoimmune diseases of complex aetiology in which the interferon (IFN) pathway plays a key role. Recent studies have reported an association between IRF7 and SLE which confers a risk to autoantibody produc...

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Main Authors: Carmona, F David, Gutala, Ramana, Simeón, Carmen P, Carreira, Patricia, Ortego-Centeno, Norberto, Vicente-Rabaneda, Esther, García-Hernández, Francisco J, de la Peña, Paloma García, Fernández-Castro, Mónica, Martínez-Estupiñán, Lina, Egurbide, María Victoria, Tsao, Betty P, Gourh, Pravitt, Agarwal, Sandeep K, Assassi, Shervin, Mayes, Maureen D, Arnett, Frank C, Tan, Filemon K, Martín, Javier
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369428/
https://ncbi.nlm.nih.gov/pubmed/21926187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-200275
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