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Evaluation of Neurodegeneration in a Mouse Model of Infantile Batten Disease by Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy

Neuronal ceroid lipofuscinoses (NCLs) represent a group of common hereditary childhood neurodegenerative storage disorders that have no effective treatment. Mutations in eight different genes cause various forms of NCLs. Infantile NCL (INCL), the most lethal disease, is caused by inactivating mutati...

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Autori principali: Munasinghe, Jeeva, Zhang, Zhongjian, Kong, Eryan, Heffer, Alison, Mukherjee, Anil B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369263/
https://ncbi.nlm.nih.gov/pubmed/22327870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334838
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