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Evaluation of Neurodegeneration in a Mouse Model of Infantile Batten Disease by Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy

Neuronal ceroid lipofuscinoses (NCLs) represent a group of common hereditary childhood neurodegenerative storage disorders that have no effective treatment. Mutations in eight different genes cause various forms of NCLs. Infantile NCL (INCL), the most lethal disease, is caused by inactivating mutati...

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Detalhes bibliográficos
Main Authors: Munasinghe, Jeeva, Zhang, Zhongjian, Kong, Eryan, Heffer, Alison, Mukherjee, Anil B.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369263/
https://ncbi.nlm.nih.gov/pubmed/22327870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334838
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