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Do cancer cells undergo phenotypic switching? The case for imperfect cancer stem cell markers

The identification of cancer stem cells in vivo and in vitro relies on specific surface markers that should allow to sort cancer cells in phenotypically distinct subpopulations. Experiments report that sorted cancer cell populations after some time tend to express again all the original markers, lea...

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Autori principali: Zapperi, Stefano, La Porta, Caterina A. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369193/
https://ncbi.nlm.nih.gov/pubmed/22679555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00441
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