An Insight into the Diverse Roles of Surfactant Proteins, SP-A and SP-D in Innate and Adaptive Immunity

Surfactant proteins SP-A and SP-D are hydrophilic, collagen-containing calcium-dependent lectins, which appear to have a range of innate immune functions at pulmonary as well as extrapulmonary sites. These proteins bind to target ligands on pathogens, allergens, and apoptotic cells, via C-terminal h...

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Bibliographic Details
Main Authors: Nayak, Annapurna, Dodagatta-Marri, Eswari, Tsolaki, Anthony George, Kishore, Uday
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369187/
https://ncbi.nlm.nih.gov/pubmed/22701116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00131
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