Exploiting sparseness in de novo genome assembly

BACKGROUND: The very large memory requirements for the construction of assembly graphs for de novo genome assembly limit current algorithms to super-computing environments. METHODS: In this paper, we demonstrate that constructing a sparse assembly graph which stores only a small fraction of the obse...

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Bibliografiske detaljer
Main Authors: Ye, Chengxi, Ma, Zhanshan Sam, Cannon, Charles H, Pop, Mihai, Yu, Douglas W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Proceedings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369186/
https://ncbi.nlm.nih.gov/pubmed/22537038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S6-S1
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