A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts

AIMS/HYPOTHESIS: In this study we aimed to replicate the previously reported association between the glycaemic response to metformin and the SNP rs11212617 at a locus that includes the ataxia telangiectasia mutated (ATM) gene in multiple additional populations. METHODS: Incident users of metformin s...

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Κύριοι συγγραφείς: van Leeuwen, N., Nijpels, G., Becker, M. L., Deshmukh, H., Zhou, K., Stricker, B. H. C., Uitterlinden, A. G., Hofman, A., van ’t Riet, E., Palmer, C. N. A., Guigas, B., Slagboom, P. E., Durrington, P., Calle, R. A., Neil, A., Hitman, G., Livingstone, S. J., Colhoun, H., Holman, R. R., McCarthy, M. I., Dekker, J. M., ’t Hart, L. M., Pearson, E. R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Springer-Verlag 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369131/
https://ncbi.nlm.nih.gov/pubmed/22453232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2537-x
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