A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts

AIMS/HYPOTHESIS: In this study we aimed to replicate the previously reported association between the glycaemic response to metformin and the SNP rs11212617 at a locus that includes the ataxia telangiectasia mutated (ATM) gene in multiple additional populations. METHODS: Incident users of metformin s...

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Hlavní autoři: van Leeuwen, N., Nijpels, G., Becker, M. L., Deshmukh, H., Zhou, K., Stricker, B. H. C., Uitterlinden, A. G., Hofman, A., van ’t Riet, E., Palmer, C. N. A., Guigas, B., Slagboom, P. E., Durrington, P., Calle, R. A., Neil, A., Hitman, G., Livingstone, S. J., Colhoun, H., Holman, R. R., McCarthy, M. I., Dekker, J. M., ’t Hart, L. M., Pearson, E. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369131/
https://ncbi.nlm.nih.gov/pubmed/22453232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2537-x
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