Efficient down-regulation of glia maturation factor expression in mouse brain and spinal cord

Long-lasting siRNA-based down-regulation of gene of interest can be achieved by lentiviral-based expression vectors driving the production of short hairpin RNA (shRNA). We investigated an attractive therapeutic approach to target the expression of proinflammatory GMF by using lentiviral vector encod...

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Bibliografiske detaljer
Main Authors: Zaheer, Smita, Wu, Yanghong, Yang, Xi, Thangavel, Ramasamy, Sahu, Shailendra K, Zaheer, Asgar
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369007/
https://ncbi.nlm.nih.gov/pubmed/22446845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0753-x
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