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Efficient down-regulation of glia maturation factor expression in mouse brain and spinal cord
Long-lasting siRNA-based down-regulation of gene of interest can be achieved by lentiviral-based expression vectors driving the production of short hairpin RNA (shRNA). We investigated an attractive therapeutic approach to target the expression of proinflammatory GMF by using lentiviral vector encod...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369007/ https://ncbi.nlm.nih.gov/pubmed/22446845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0753-x |
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