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Efficient down-regulation of glia maturation factor expression in mouse brain and spinal cord

Long-lasting siRNA-based down-regulation of gene of interest can be achieved by lentiviral-based expression vectors driving the production of short hairpin RNA (shRNA). We investigated an attractive therapeutic approach to target the expression of proinflammatory GMF by using lentiviral vector encod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zaheer, Smita, Wu, Yanghong, Yang, Xi, Thangavel, Ramasamy, Sahu, Shailendra K, Zaheer, Asgar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369007/
https://ncbi.nlm.nih.gov/pubmed/22446845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0753-x
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