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FLT3 Mutation Status is a Predictor of Early Death in Pediatric Acute Promyelocytic Leukemia: A Report From The Children's Oncology Group

BACKGROUND: FLT3 mutations (FLT3/Mut) are prevalent in de novo AML and are associated with early relapse. The prevalence and prognostic significance of FLT3/Mut have not been well defined in childhood acute promyelocytic leukemia (APL). PROCEDURE: Diagnostic specimens from 104 pediatric APL patients...

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Bibliographische Detailangaben
Hauptverfasser: Kutny, Matthew A., Moser, Barry K., Laumann, Kristina, Feusner, James H., Gamis, Alan, Gregory, John, Larson, Richard A., Powell, Bayard L., Stock, Wendy, Willman, Cheryl L., Woods, William G., Meshinchi, Soheil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368997/
https://ncbi.nlm.nih.gov/pubmed/22378655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24122
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