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Ouabain-induced cochlear degeneration in rat

Ouabain, an potent inhibitor of the Na+/K+-ATPase pump, selectively destroys spiral ganglion neurons (SGNs) in gerbils and mice whereas in guinea pigs it preferentially damages cochlear hair cells. To elucidate the effects of ouabain on the rat inner ear, a species widely used in research, 5 µl of 1...

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Detalhes bibliográficos
Main Authors: Fu, Yong, Ding, Dalian, Jiang, Haiyan, Salvi, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368987/
https://ncbi.nlm.nih.gov/pubmed/22476946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-012-9320-0
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