Combined Blockade of ADP Receptors and PI3-Kinase p110β Fully Prevents Platelet and Leukocyte Activation during Hypothermic Extracorporeal Circulation

Extracorporeal circulation (ECC) and hypothermia are used to maintain stable circulatory parameters and improve the ischemia tolerance of patients in cardiac surgery. However, ECC and hypothermia induce activation mechanisms in platelets and leukocytes, which are mediated by the platelet agonist ADP...

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מידע ביבליוגרפי
Main Authors: Krajewski, Stefanie, Kurz, Julia, Geisler, Tobias, Peter, Karlheinz, Wendel, Hans Peter, Straub, Andreas
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368839/
https://ncbi.nlm.nih.gov/pubmed/22701645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038455
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