Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation.

Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass activates leukocytes and platelets; however the contribution of early (3a) versus late (C5a, soluble C5b-9) complement components to this activatio...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Rinder, C S, Rinder, H M, Smith, B R, Fitch, J C, Smith, M J, Tracey, J B, Matis, L A, Squinto, S P, Rollins, S A
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118195
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