Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation.

Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass activates leukocytes and platelets; however the contribution of early (3a) versus late (C5a, soluble C5b-9) complement components to this activatio...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rinder, C S, Rinder, H M, Smith, B R, Fitch, J C, Smith, M J, Tracey, J B, Matis, L A, Squinto, S P, Rollins, S A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118195
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