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Selective DNA demethylation by fusion of TDG with a sequence-specific DNA-binding domain
Our ability to selectively manipulate gene expression by epigenetic means is limited, as there is no approach for targeted reactivation of epigenetically silenced genes, in contrast to what is available for selective gene silencing. We aimed to develop a tool for selective transcriptional activation...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368818/ https://ncbi.nlm.nih.gov/pubmed/22419066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19509 |
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