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Mitochondrial regulation of epigenetics and its role in human diseases
Most pathogenic mitochondrial DNA (mtDNA) mutations induce defects in mitochondrial oxidative phosphorylation (OXPHOS). However, phenotypic effects of these mutations show a large degree of variation depending on the tissue affected. These differences are difficult to reconcile with OXPHOS as the so...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368816/ https://ncbi.nlm.nih.gov/pubmed/22419065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19547 |
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