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Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods

Efficient intracellular delivery is essential for high activity of nucleic acids based therapeutics, including antisense agents. Several strategies have been developed and practically all rely on auxiliary transfection reagents such as cationic lipids, cationic polymers and cell penetrating peptides...

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Bibliographic Details
Main Authors: Llovera, Laia, Berthold, Peter, Nielsen, Peter E., Shiraishi, Takehiko
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368813/
https://ncbi.nlm.nih.gov/pubmed/22679530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.19906
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