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Efficiency of Cellular Delivery of Antisense Peptide Nucleic Acid by Electroporation Depends on Charge and Electroporation Geometry

Electroporation is potentially a very powerful technique for both in vitro cellular and in vivo drug delivery, particularly relating to oligonucleotides and their analogs for genetic therapy. Using a sensitive and quantitative HeLa cell luciferase RNA interference mRNA splice correction assay with a...

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Detalhes bibliográficos
Main Authors: Joergensen, Mette, Agerholm-Larsen, Birgit, Nielsen, Peter E., Gehl, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045790/
https://ncbi.nlm.nih.gov/pubmed/21235293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2010.0266
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