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Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4(+)Foxp3(+) regulatory T cells in the establishment of oral tolerance

Oral tolerance is a key feature of intestinal immunity, generating systemic tolerance to fed antigens. However, the molecular mechanism mediating oral tolerance remains unclear. In this study, we examined the role of the B7 family members of costimulatory molecules in the establishment of oral toler...

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Bibliografiske detaljer
Main Authors: Fukaya, Tomohiro, Takagi, Hideaki, Sato, Yumiko, Sato, Kaori, Eizumi, Kawori, Taya, Honami, Shin, Tahiro, Chen, Lieping, Dong, Chen, Azuma, Miyuki, Yagita, Hideo, Malissen, Bernard, Sato, Katsuaki
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368550/
https://ncbi.nlm.nih.gov/pubmed/20574047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-250472
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